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Case Report
Online Published: 20 Jun 2026
 


Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes

Mitkumar Prajapati, Anitha Hosur And Anjali Gambhava.


Abstract
Background: Decompensated liver cirrhosis represents an advanced stage of chronic liver disease characterised by portal hypertension, ascites, and impaired hepatic function. Conventional management primarily focuses on symptomatic relief through diuretics and paracentesis, with limited reversal of disease progression. In Ayurveda, this condition can be correlated with Yakritodara (hepatomegaly) progressing to Jalodara, (ascites) involving derangement of Agni (metabolism) and obstruction of Srotas. (body channels) Objective: to evaluate the clinical outcomes of an Ayurveda interventions in refractory decompensated cirrhosis using biochemical, radiological, and Child–Pugh prognostic parameters. Case Details: A 58-year-old male with a history of Type 2 Diabetes Mellitus and Hypertension presented with abdominal distension, scleral icterus, and Grade 3 bilateral pedal oedema. Despite standard allopathic treatment, symptoms persisted. The patient was managed with a four-week Ayurveda regimen which included Nitya Virechana (daily purgation with Trivrutastak Churna), Patoladi Kwatha, Mahatikta Ghrita, and Indrayavadi Vati internally, along with dietary regulation. Results: Clinical assessment demonstrated reduction in abdominal girth and pedal oedema. Biochemical parameters showed improvement, with total bilirubin decreasing from 4.96 mg/dL to 2.58 mg/dL and normalisation of transaminases. Ultrasonography revealed reduction in ascitic fluid from moderate–gross to mild. Child–Pugh score improved from Class C (10) to Class B (8). Conclusion: This case report demonstrates that Ayurveda management may contribute to improvement in clinical and biochemical parameters in refractory decompensated cirrhosis. Further controlled studies are required to validate these findings.

Key words: Ayurveda, Decompensated Cirrhosis, Child–Pugh Score, Ascites, Case Report


 
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Pubmed Style

Prajapati M, Gambhava AHAA. Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes. J. res. tradit. med. Online First: 20 Jun, 2026. doi:10.5455/jrtm.2026-312366


Web Style

Prajapati M, Gambhava AHAA. Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes. https://www.tmjournal.org/?mno=312366 [Access: June 25, 2026]. doi:10.5455/jrtm.2026-312366


AMA (American Medical Association) Style

Prajapati M, Gambhava AHAA. Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes. J. res. tradit. med. Online First: 20 Jun, 2026. doi:10.5455/jrtm.2026-312366



Vancouver/ICMJE Style

Prajapati M, Gambhava AHAA. Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes. J. res. tradit. med, [cited June 25, 2026]; Online First: 20 Jun, 2026. doi:10.5455/jrtm.2026-312366



Harvard Style

Prajapati, M. & Gambhava, . A. H. A. A. (2026) Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes. J. res. tradit. med, Online First: 20 Jun, 2026. doi:10.5455/jrtm.2026-312366



Turabian Style

Prajapati, Mitkumar, and Anitha Hosur And Anjali Gambhava. 2026. Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes. JOURNAL OF RESEARCH IN TRADITIONAL MEDICINE, Online First: 20 Jun, 2026. doi:10.5455/jrtm.2026-312366



Chicago Style

Prajapati, Mitkumar, and Anitha Hosur And Anjali Gambhava. "Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes." JOURNAL OF RESEARCH IN TRADITIONAL MEDICINE Online First: 20 Jun, 2026. doi:10.5455/jrtm.2026-312366



MLA (The Modern Language Association) Style

Prajapati, Mitkumar, and Anitha Hosur And Anjali Gambhava. "Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes." JOURNAL OF RESEARCH IN TRADITIONAL MEDICINE Online First: 20 Jun, 2026. Web. 25 Jun 2026 doi:10.5455/jrtm.2026-312366



APA (American Psychological Association) Style

Prajapati, M. & Gambhava, . A. H. A. A. (2026) Ayurvedic Management of Refractory Decompensated Cirrhosis: A Case Report with Clinical and Biochemical Outcomes. JOURNAL OF RESEARCH IN TRADITIONAL MEDICINE, Online First: 20 Jun, 2026. doi:10.5455/jrtm.2026-312366